Pillars of Eternity 2: Deadfire speedrun (26:25) (Path of the Damned, with Blessings)
For the people who do read descriptions:
Blessings are mainly used because they make the run less tedious: they mainly cut down on time spent duping gold. It'd take several minutes longer to obtain 105,000 gold without the Blessings.
Path of the Damned is maybe a couple seconds faster than easy because you can lose the boat fight so quickly. Downside is the dragons at Ashen Maw being a lot more annoying, but it's worth it.
Some run comments:
Killing Eder at the start is required to stop him from